產(chǎn)品屬性：
產(chǎn)品名稱 | WWL229 |
規(guī)格 | 1mg、5mg、10mg、25mg |
貨號 | EY-01Y17988 |
Cas No.: 1338575-28-2
別名: N/A
化學名: N/A
分子式: C16H22N2O5
分子量: 322.4
溶解度: DMF: 30 mg/ml,DMSO: 25 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Mouse carboxylesterase 3 (Ces3, also named Ces1d) mediates triglyceride hydrolysis in white adipose tissue, liberating free fatty acids into circulation. Although important for basal lipolysis, Ces3 expression can be induced by xenobiotics. Ces3 activity is significantly elevated during adipocyte differentiation. WWL229 is a selective inhibitor of Ces3 (IC50 = 1.94 μM) that has no significant effect on other, related enzymes. By inhibiting the triglyceride hydrolase activity of Ces3, WWL229 promotes lipid storage in cultured adipocytes and prevents basal lipolysis.
特別提醒公司產(chǎn)品僅供科研使用
