產(chǎn)品屬性:
產(chǎn)品名稱 | VTP-27999 Hydrochloride |
規(guī)格 | 2mg、5mg、10mM*1mL in Water、50mg、100mg、200mg、500mg |
貨號 | EY-01Y17371 |
Cas No.: 1264191-73-2
別名: N/A
化學名: N/A
分子式: C26H42Cl2N4O5
分子量: 561.54
溶解度: H2O: ≥ 100 mg/mL (178.08 mM)
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述:
VTP-27999 Hcl is an alkyl amine Renin inhibitor; VTP-27999 is useful for Hypertension and End-Organ Diseases.IC50 value:Target: Renin[1]. Lanqi Jia et al. Discovery of VTP-27999, an Alkyl Amine Renin Inhibitor with Potential for Clinical Utility ACS Med. Chem. Lett., 2011, 2 (10), pp 747-751
[2]. New renin inhibitor VTP-27999 alters renin immunoreactivity and does not unfold prorenin. Hypertension. 2013 May;61(5):1075-1082.
[3]. Ishchenko A, et al. Structure-based design technology contour and its application to the design of Renin inhibitors.J Chem Inf Model. 2012 Aug 27;52(8):2089-97. Epub 2012 Jul 25.
特別提醒公司產(chǎn)品僅供科研使用