產(chǎn)品屬性：
產(chǎn)品名稱 | VU 6001966 |
規(guī)格 | 5 mg |
貨號 | EY-01Y15776 |
Cas No.: 2009052-76-8
別名: N/A
化學名: N/A
分子式: C17H15FN4O2
分子量: 326.33
溶解度: Soluble in DMSO
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Potent and selective mGlu2 negative allosteric modulator (IC50 = 78 nM). Exhibits > 350-fold selectivity for mGlu2 over mGlu3. Also exhibits selectivity over other mGluRs and a panel of GPCRs, ion channels and transporters. CNS penetrant.Bollinger et al (2017) Design and synthesis of mGlu2 NAMs with improved potency and CNS penetration based on a truncated picolinamide core. ACS Med.Chem.Lett. 8 919 PMID:28947937
特別提醒公司產(chǎn)品僅供科研使用
