產品屬性:
產品名稱 | Picamilon |
規(guī)格 | 100mg、250mg、500mg、1g |
貨號 | EY-01Y14541 |
Cas No.: 34562-97-5
別名: N/A
化學名: N/A
分子式: C10H12N2O3
分子量: 208.2
溶解度: DMSO: 1 mg/ml,DMSO:PBS (pH 7.2) (1:9): 0.10 mg/ml
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述:
Picamilon is a derivative of γ-aminobutyric acid (GABA).1 It increases parietal cortical blood flow in rats and rabbits when administered at doses of 50 mg/kg, i.p. and 10 mg/kg, i.v., respectively.2 Picamilon (10 mg/kg) increases latency to enter the dark compartment in the passive avoidance conditioned reflex test in rats compared with control animals, indicating nootropic effects.1|1. Kopelevich, V.M., Bulanova, L.N., Grigor'ev, I.A., et al. Synthesis and study of psychotropic and hypotensive properties of new picamilon derivatives. Pharm. Chem. J. 31(10), 536-539 (1997).|2. Mirzoyan, R.S., Gan'shina, T.S., Kosoi, M.Y., et al. Effect of picamilon on the cerebral cortical blood supply and microcirculation in the pial arteriolar system. Biull. Eksp. Biol. Med. 107(5), 668-670 (1989).
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