產(chǎn)品屬性：
產(chǎn)品名稱 | Zaurategrast ethyl ester sulfate |
規(guī)格 | 5mg、10mg、25mg |
貨號 | EY-01Y14224 |
Cas No.: 1214261-78-5
別名: N/A
化學名: N/A
分子式: C28H29BrN4O3.1/2H2O4S
分子量: 647.54
溶解度: Soluble in DMSO
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Zaurategrast ethyl ester sulfate (CDP323 sulfate), the ethyl ester prodrug of CT7758[1], is a α4β1/α4β7 integrin antagonist used for the treatment of inflammatory and autoimmune disorders[2].α4β1/α4β7 integrin[1]Zaurategrast ethyl ester sulfate (CDP323 sulfate), an ethyl ester prodrug of CT7758, shows some improvements in increasing mass transfer[1].[1]. Chanteux H, et al. Cross-Species Differences in the Preclinical Pharmacokinetics of CT7758, an α4β1/α4β7 Integrin Antagonist. Drug Metab Dispos. 2015 Sep;43(9):1381-91.
[2]. Davenport RJ, et al. Alpha4-integrin antagonism--an effective approach for the treatment of inflammatory diseases? Drug Discov Today. 2007 Jul;12(13-14):569-76.
特別提醒公司產(chǎn)品僅供科研使用
