產(chǎn)品屬性：
產(chǎn)品名稱 | Zearalenone-13C18 |
規(guī)格 | 1.2 ml |
貨號 | EY-01Y13662 |
Cas No.: 911392-43-3
別名: N/A
化學(xué)名: N/A
分子式: [13C]18H22O5
分子量: 336.2
溶解度: Acetonitrile: soluble
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Zearalenone-13C18 is intended for use as an internal standard for the quantification of zearalenone by GC- or LC-MS. Zearalenone is a mycotoxin that has been found in Fusarium and has estrogenic activities.1 It binds to human estrogen receptor α (ERα) and ERβ (IC50s = 9 and 5.8 nM, respectively).2 Zearalenone induces precocious development of mammary tissues in young female pigs and prepucial enlargement in young male pigs.3 Zearalenone (1.5-5 mg/kg of diet) induces hyperestrogenism in pigs. It also induces degeneration of meiotic chromatin in oocytes and reduces fertility in pigs when administered at a dose of 200 μg/kg.4 Zearalenone has been found as a contaminant in wheat, maize, and barley and livestock feeds.3,41.Zinedine, A., Soriano, J.M., Moltó, J.C., et al.Review on the toxicity, occurrence, metabolism, detoxification, regulations and intake of zearalenone: An oestrogenic mycotoxinFood Chem. Toxicol.45(1)1-18(2007)
2.Kuiper, G.G.J.M., Lemmen, J.G., Carlsson, B., et al.Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor βEndocrinology139(10)4252-4263(1998)
3.Richard, J.L.Some major mycotoxins and their mycotoxicoses—an overviewInt. J. Food Microbiol.119(1-2)3-10(2007)
4.Tiemann, U., and D?nicke, S.In vivo and in vitro effects of the mycotoxins zearalenone and deoxynivalenol on different non-reproductive and reproductive organs in female pigs: A reviewFood Addit. Contam.24(3)306-314(2007)
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