產(chǎn)品屬性：
產(chǎn)品名稱 | XL092 |
規(guī)格 | 10mM*1 mL in DMSO、5 mg、10 mg、25 mg、50 mg |
貨號(hào) | EY-01Y12772 |
Cas No.: 2367004-54-2
別名: N/A
化學(xué)名: N/A
分子式: C29H25FN4O5
分子量: 528.53
溶解度: DMSO : 25 mg/mL (47.30 mM; Need ultrasonic)
儲(chǔ)存條件: 4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
XL092 is a potent inhibitor of the activity of Axl, Mer and C-Met kinase with IC50s of <10 nM, respectively. XL092 exhibits anti-tumor activity and has the potential for kinase-dependent diseases and conditions research[1].XL092 (compound 8; 3 mg/kg; iv) has a T1/2 of 5.4 hours, a CL of 43 mL/hr?kg. XL092 (3 mg/kg; po) has a T1/2 of 7.1 hours and a Cmax of 11.4 μM for rats[1].[1]. Lynne Canne Bannen, et al. Compounds for the treatment of kinase-dependent disorders. WO2019148044A1.
特別提醒公司產(chǎn)品僅供科研使用
