產(chǎn)品屬性:
產(chǎn)品名稱 | Antileukinate |
規(guī)格 | 500μg、1mg、5mg |
貨號 | EY-01Y12175 |
Cas No.: 138559-60-1
別名: N/A
化學(xué)名: N/A
分子式: C45H66N18O7S
分子量: 1003.2
溶解度: DMF: 1 mg/ml,DMSO: 5 mg/ml,PBS (pH 7.2): 2 mg/ml
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述:
Antileukinate is a synthetic hexapeptide with an acetylated amino terminus and an amidated carboxyl terminus that inhibits the binding of CXC chemokines to the chemokine receptor CXCR2. It inhibits IL-8 binding to neutrophils (Ki = 2.7-13 μM), prevents neutrophil chemotaxis and β-glucuronidase release, and blocks IL-8-induced skin edema in rabbits. At 53 mg/kg, antileukinate has been shown to protect mice against acute pancreatitis and associated lung injury.
特別提醒公司產(chǎn)品僅供科研使用