產(chǎn)品屬性：
產(chǎn)品名稱 | Neuromedin N |
規(guī)格 | 5mg、10mM*1mL in Water25mg、50mg、100mg |
貨號 | EY-01Y12192 |
Cas No.: 92169-45-4
別名: N/A
化學名: N/A
分子式: C38H63N7O8
分子量: 745.95
溶解度: H2O: 50 mg/mL (67.03 mM)
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Neuromedin N is a potent modulator of dopamine D2 receptor agonist binding in rat neostriatal membranes.Dopamine D2 receptor[1].Neuromedin N competitively inhibits the binding of neurotensin to rat brain synaptic membranes with a 19-fold lower potency than neurotensin and is rapidly inactivated by brain synaptic peptidases[1]. It competitively inhibits neurotensin binding to rat brain synaptic membranes and has increased potency in the presence of the peptidase inhibitor bestatin[2].[1]. Li XM, et al. Neuromedin N is a potent modulator of dopamine D2 receptor agonist binding in rat neostriatal membranes. Neurosci Lett. 1993 Jun 11;155(2):121-4.
[2]. Checler F, et al. Neuromedin N: high affinity interaction with brain neurotensin receptors and rapid inactivation by brain synaptic peptidases. Eur J Pharmacol. 1986 Jul 31;126(3):239-44.
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