產(chǎn)品屬性:
產(chǎn)品名稱 | Lanreotide (acetate) |
規(guī)格 | 1mg、5mg、10mg |
貨號(hào) | EY-01Y11921 |
Cas No.: 127984-74-1
別名: N/A
化學(xué)名: N/A
分子式: C54H69N11O10S2?XC2H4O2
分子量: 1096.3
溶解度: DMSO: Slightly Soluble,Methanol: Slightly Soluble
儲(chǔ)存條件: Store at -20°C, protect from light, stored under nitrogen
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述:
Lanreotide is a peptide analog of somatostatin that binds to somatostatin receptors (SSTRs) with a higher affinity for the somatostatin subgroup 2 receptors SST2, SST3, and SST5 (IC50s = 0.5-1.8, 43-107, and 5.6-32 nM, respectively) than for the subgroup 1 receptors, SST1 and SST4 (IC50s = 500-2,330 and 66-2,100 nM, respectively). Lanreotide (100 nM) inhibits the release of growth hormone from patient-derived pituitary adenoma cells in vitro. It also inhibits tumor growth in human small cell lung cancer (SCLC) mouse xenograft models when administered at a dose of 250 μg, twice daily. Formulations containing lanreotide have been used in the treatment of acromegaly and neuroendocrine tumors.
特別提醒公司產(chǎn)品僅供科研使用