產(chǎn)品屬性:
產(chǎn)品名稱 | S3QEL-2 |
規(guī)格 | 5mg、10mg、25mg |
貨號 | EY-01Y11005 |
Cas No.: 890888-12-7
別名: N/A
化學(xué)名: 1-(3,4-dimethylphenyl)-N,N-dipropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
分子式: C19H25N5
分子量: 323.4
溶解度: 10mg/mL in DMF, Slightly soluble in DMSO
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述:
S3QEL-2 is a cell-permeable, selective suppressor of electron leak from mitochondrial respiratory complex III, inhibiting site IIIQo superoxide production (IC50 = 1.7 μM) without altering normal bioenergetics function.[1] It reduces production of H2O2 during oxidation of glutamate plus malate to 25% of the control level. S3QEL-2 also protects against ROS-induced cell stress in pancreatic β-cells and decreases HIF-1α induction in response to hypoxia.
特別提醒公司產(chǎn)品僅供科研使用