產(chǎn)品屬性：
產(chǎn)品名稱 | W140 (trifluoroacetate salt) |
規(guī)格 | 500μg、1mg、5mg、10mg |
貨號 | EY-01Y10542 |
Cas No.: 909725-64-0
別名: N/A
化學名: N/A
分子式: C16H27N2O4P?CF3COOH
分子量: 456.4
溶解度: Ethanol: 0.15 mg/ml
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Sphingosine-1-phosphate (S1P) is a bioactive lipid that exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis. It exerts its activity by binding to five distinct G protein-coupled receptors, S1P1/EDG-1, S1P2/EDG-5, S1P3/EDG-3, S1P4/EDG-6, and S1P5/EDG-8. W140 is an inactive enantiomer of W146, a selective S1P1 antagonist (Ki = 77 nM), that binds to the S1P1 receptor with a Ki of 4.6 μM (2a = W146; 2b = W140 in supplemental material). It exhibits no biological activity in vivo and can therefore serve as an effective control compound for experiments involving W146.
特別提醒公司產(chǎn)品僅供科研使用
